Clinton elicited laughter from the audience when she admitted that ''the Republicans have a core group that, I think is fair to say, are not my fans.''
She was asked by reporters about her recent criticism of other Democrats, when earlier this year she called for her party to focus their attacks on Republicans.
''I respect and admire all of my opponents, and I think that there are differences among us on issues and on qualifications and on experience,'' she said. ''When we finally choose a nominee, which I expect to be me, we are going to close ranks, and we are going to run against the Republicans and win.''
Barack Obama's campaign weighed in, claiming he is the strongest candidate in the field.
''Throughout his career, Senator Obama has succeeded in bringing Democrats, Republicans and independents together to solve important problems like providing health care to families,'' Obama spokesman Tommy Vietor said.
A recent Washington Post-ABC News poll showed Obama had 30 percent support among likely Iowa Democratic caucus-goers and Clinton had 26 percent. She leads in many other national polls.
When asked about Obama's lead in Iowa, Clinton answered that she doesn't pay much attention to polls, and acknowledged that it's a competitive race.
''There have been a lot of polls, and frankly, I don't pay much attention to any of them,'' she said. Later, she acknowledged, ''It is a much more competitive race (in Iowa) than it is in other parts of the country.''
Clinton, who wants a withdrawal of troops from Iraq, was asked whether she thought the surge there is working. She told reporters she doesn't believe there is a military solution for Iraq.
''I don't believe if we stay another day, stay five days, stay five years or 10 years that we are going to make a difference militarily,'' she said. ''Yes, we can have some tactical successes, but ultimately this is up to the Iraqis. I believe we should start bringing our troops home now.''