Erickson Tribune

Health Secrets

UPDATED: Thursday, January 03, 2008

Is it thyroid disease or are you just getting older?

Posted on Thursday, January 03, 2008
 

By Lisa M. Davila
THE ERICKSON TRIBUNE

Jack is an 82-year-old grandfather who has been taking extra naps lately and gaining some weight. Mary is a 75-year-old retired English teacher who has been feeling weak, especially in her legs when she climbs stairs. Nancy is an 87-year-old great-grandmother who has slowly lost her appetite and occasionally feels “fluttering” in her chest.

All of these people have something in common: thyroid disease.

Your thyroid gland is small, shaped like a bow tie, and located just above your collarbone.  It produces hormones that regulate the rate at which your body carries out its necessary functions.

The symptoms of thyroid disease in older adults may not be obvious.  Symptoms of thyroid disease in older adults can be similar to signs of normal aging like fatigue, appetite changes, or behavior changes,” says Sally M. Pinkstaff, M.D., endocrinologist and geriatric specialist at Sinai Hospital in Baltimore, Md.

The most common thyroid diseases are hyperthyroidism (an overactive thyroid) and hypothyroidism (an underactive thyroid). Both conditions can have similar symptoms.

Hyperthyroidism
Hyperthyroidism occurs when too much thyroid hormone is produced. This, in turn, causes bodily functions to speed up.

A common cause of hyperthyroidism in older adults is toxic nodular or multinodular goiter. “The ‘goiter’ refers to an enlarged thyroid gland,” Pinkstaff says. Sometimes it produces too much thyroid hormone. “But a multinodular goiter can be present without causing a hyperactive thyroid,” she adds.

Older adults may only have one or two symptoms of an overactive thyroid.  Approximately one out of three to one out of four older adults who have hyperthyroidism will have heart palpitations as their only symptom,” says Martin I. Surks, M.D., program director of the Montefiore Medical Center’s division of endocrinology and metabolism, New York, N.Y. “Another symptom might be weight loss, because with an veractive thyroid, you tend to metabolize food at a more rapid rate.”


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Treatment for hyperthyroidism may involve antithyroid medication or radioactive iodine treatment (a one-time pill), depending on your doctor’s recommendations. Surgery may be an option, depending on your health. People successfully treated for an overactive thyroid sometimes develop an underactive one. “Someone with hyperthyroidism might have symptoms that seem more typical of hypothyroidism,” Pinkstaff says.

Hypothyroidism
Hypothyroidism occurs when the thyroid gland stops producing enough thyroid hormone. The incidence of hypothyroidism increases with age. By age 60, as many as 17% of women and 9% of men have an underactive thyroid. Hypothyroidism is treated by taking the thyroid hormone in pill form.

The symptoms of hypothyroidism can be nonspecific. “People with  hypothyroidism might feel tired, bloated, cold, constipated, or they may have a depressed mood or forgetfulness,” Surks says. “Hypothyroidism’s onset can be so gradual, people may barely notice the symptoms,” Pinkstaff adds.

It’s important to treat a severely malfunctioning thyroid. While most people may not give much thought to this little gland, a malfunctioning thyroid can have significant health consequences.

Thyroid disease and other health conditions
Fluctuating thyroid levels can adversely affect your heart, especially if you already have any type of heart disease. “Conditions like angina, heart failure, or rhythm disturbances can worsen with thyroid disease,” Surks says. Pinkstaff adds, “With hyperthyroidism, osteoporosis can worsen. And if your muscles are weak, you can be at an increased risk for falls.”

“Other common conditions that can be caused or aggravated by thyroid disease are depression or anxiety,” says Mark Holden, M.D., Erickson Health physician at Eagle’s Trace, an Erickson-built and -managed community in Houston, Tex.

Important medication considerations
“Medications for hyperthyroidism, like propylthiouracil or methimazole, can suppress the immune system,” Holden says. “It’s not a common side effect, but it’s a serious one. If you’re taking one of these drugs and you develop a fever, sore throat, or any other sign of infection, you need to contact your health care provider right away.”

Levothyroxine is also commonly prescribed for hypothyroidism. “The main problem with this drug is getting the dose just right,” says Surks. Holden adds, “Antacids, and other medications that change the acid balance in your stomach, can affect the way levothyroxine is absorbed.” Some foods, like soy and  high-fiber products, may also affect absorption.

Since absorption of levothyroxine can vary, you should tell your doctor if your pharmacy changes your medication from a brand name (Synthroid, Levothroid, Levoxyl) to the generic, or if your pharmacy changes generic manufacturers. If your medication changes, your doctor may recommend a blood test after a few months to make sure your thyroid hormone levels are stable.

A different type of hypothyroidism
Many older adults who have no symptoms are diagnosed with hypothyroidism simply through a routine annual blood test. Their actual thyroid hormone levels (T4) might be normal, but they have mildly elevated levels of thyroid stimulating hormone (TSH)—a condition known as subclinical hypothyroidism.

“Surveys have shown that up to 10% or 15% of people in their 70s and 80s have  subclinical hypothyroidism,” Surks says. “It’s also been shown, however, that up to half of people with subclinical hypothyroidism will have normal TSH levels after a period of time without any treatment. So it’s not unreasonable for you to ask for a recheck of your blood work prior to starting a medication that you’ll be taking for the rest of your life.”



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